# OmniProt™ Plasma/Serum Low Abundance Protein Enrichment Kit
## Introduction
The OmniProt™ Plasma/Serum Low Abundance Protein Enrichment Kit is a revolutionary tool designed to address one of the most challenging aspects of proteomics research – the detection and analysis of low-abundance proteins in plasma and serum samples. This innovative kit provides researchers with a reliable and efficient method to enrich these elusive proteins, opening new possibilities for biomarker discovery and disease research.
## Key Features
The OmniProt™ kit offers several advantages for proteomic studies:
– High-efficiency enrichment of low-abundance proteins
– Compatibility with mass spectrometry analysis
– Simple and straightforward protocol
– Reproducible results across multiple samples
– Minimal sample loss during processing
## Technical Specifications
The kit contains all necessary components for protein enrichment:
Component | Quantity
Depletion Column | 10 columns
Binding Buffer | 100 mL
Elution Buffer | 50 mL
Wash Buffer | 100 mL
Storage Buffer | 50 mL
## Applications
This enrichment kit has wide-ranging applications in biomedical research:
### Biomarker Discovery
Enables detection of potential disease markers present at low concentrations in blood samples.
### Clinical Proteomics
Facilitates the study of protein profiles in various disease states.
### Drug Development
Supports pharmacokinetic studies and drug target identification.
## Protocol Overview
The standard workflow involves three main steps:
– Sample preparation and conditioning
– Column-based depletion of high-abundance proteins
– Enrichment and collection of low-abundance proteins
The entire process can be completed in approximately 2 hours, making it suitable for high-throughput studies.
## Performance Data
Independent validation studies have demonstrated:
– >95% depletion of major plasma proteins
– 10-100x enrichment of low-abundance proteins
– Excellent reproducibility (CV < 15%)
– Compatibility with downstream LC-MS/MS analysis
## Ordering Information
The OmniProt™ Plasma/Serum Low Abundance Protein Enrichment Kit is available in two sizes:
– Standard Kit (10 columns) – Catalog #OP-PS100
– Large Scale Kit (50 columns) – Catalog #OP-PS500
For researchers requiring custom configurations or bulk orders, please contact our technical support team.
## Technical Support
Our team of proteomics experts provides comprehensive support, including:
– Protocol optimization
– Troubleshooting assistance
– Data interpretation guidance
– Custom method development
The OmniProt™ Plasma/Serum Low Abundance Protein Enrichment Kit represents a significant advancement in proteomics research tools. By effectively addressing the challenge of low-abundance protein detection, this kit empowers researchers to explore previously inaccessible regions of the plasma proteome, potentially leading to groundbreaking discoveries in human health and disease.
